Mason Stephen E, DeVilliers Patricia, Andea Aleodor A
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249-6815, USA.
J Cutan Pathol. 2009 Aug;36(8):906-9. doi: 10.1111/j.1600-0560.2008.01133.x.
Lymphedematous fibroepithelial polyps of the penis are lesions that have only recently been described and are frequently associated with condom catheter use. We report an additional case of lymphedematous fibroepithelial polyps of the penis in association with long-term condom catheter use in a 36-year-old man. Local excision showed large polypoid nodules with compact orthohyperkeratosis and mild acanthosis. The stroma was hypercellular with spindled to stellate fibroblasts and occasional multinucleated cells. Proliferation of small linear to slightly arcuate vessels with some superficial dilatation was a prominent feature. Focal expression of smooth muscle actin and desmin was present in the stroma. Lymphedematous fibroepithelial polyps of the penis are rare lesions with only 11 cases previously reported. We present here an additional example of this entity to highlight the differential diagnosis, the association with condom catheter use and to raise awareness for this unusual diagnosis.
阴茎淋巴水肿性纤维上皮性息肉是一种最近才被描述的病变，常与避孕套导管的使用有关。我们报告了一例36岁男性因长期使用避孕套导管而出现阴茎淋巴水肿性纤维上皮性息肉的病例。局部切除显示有大的息肉样结节，伴有致密的正角化过度和轻度棘皮症。间质细胞增多，有成梭形至星状的成纤维细胞以及偶尔的多核细胞。小的线性至轻度弓形血管增生并伴有一些表面扩张是一个突出特征。间质中存在平滑肌肌动蛋白和结蛋白的局灶性表达。阴茎淋巴水肿性纤维上皮性息肉是罕见病变，此前仅报告过11例。我们在此展示该实体的另一个病例，以突出鉴别诊断、与避孕套导管使用的关联，并提高对这种不寻常诊断的认识。
