Ponseti J, Kropp P, Bosinski H A
Section of Sexual Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany.
Int J Impot Res. 2009 Sep-Oct;21(5):292-300. doi: 10.1038/ijir.2009.31. Epub 2009 Jul 9.
The aim of this study was to elucidate the brain processes preceding penile responses. Electroencephalographic (EEG) potentials and penile circumference were recorded simultaneously while male subjects were exposed to visual sexual stimuli (VSS). The trials were sorted by the penile response of the subjects (erection, maintenance or detumescence). The corresponding EEG recordings were then subjected to independent component analysis. We found that 200 ms after VSS onset brain potentials differ according to the genital response to follow. Whereas early posterior negativity (EPN) was predominantly related to erection and maintenance, P3-like activity was found to precede detumescence. EPN indicates a more 'emotional' processing state of the brain, whereas P3-like activity related to detumescence indicates a more 'cognitive' processing state. The latter is assumed to reflect activity of the locus coeruleus-norepinephrine system. Further research should evaluate the contribution of P3-related brain activity to psychogenic erectile dysfunction.
本研究的目的是阐明阴茎反应之前的大脑过程。在男性受试者暴露于视觉性刺激（VSS）时，同时记录脑电图（EEG）电位和阴茎周长。试验根据受试者的阴茎反应（勃起、维持或消肿）进行分类。然后对相应的EEG记录进行独立成分分析。我们发现，在VSS开始后200毫秒，脑电位根据随后的生殖器反应而有所不同。早期后负波（EPN）主要与勃起和维持有关，而类似P3的活动则在消肿之前出现。EPN表明大脑处于一种更“情绪化”的处理状态，而与消肿相关的类似P3的活动表明大脑处于一种更“认知”的处理状态。后者被认为反映了蓝斑-去甲肾上腺素系统的活动。进一步的研究应评估与P3相关的大脑活动对心因性勃起功能障碍的作用。
