Department of Forensic Psychiatry, University Hospital of Psychiatry Zurich, Alleestrasse 61A, 8462, Rheinau, Switzerland.
Department of Forensic Psychiatry, University Hospital of Psychiatry Zurich, Zurich, Switzerland.
Arch Sex Behav. 2023 Feb;52(2):497-596. doi: 10.1007/s10508-019-01547-3. Epub 2020 Feb 3.
Many reviews on sexual arousal in humans focus on different brain imaging methods and behavioral observations. Although neurotransmission in the brain is mainly performed through electrochemical signals, there are no systematic reviews of the electrophysiological correlates of sexual arousal. We performed a systematic search on this subject and reviewed 255 studies including various electrophysiological methods. Our results show how neuroelectric signals have been used to investigate genital somatotopy as well as basic genital physiology during sexual arousal and how cortical electric signals have been recorded during orgasm. Moreover, experiments on the interactions of cognition and sexual arousal in healthy subjects and in individuals with abnormal sexual preferences were analyzed as well as case studies on sexual disturbances associated with diseases of the nervous system. In addition, 25 studies focusing on brain potentials during the interaction of cognition and sexual arousal were eligible for meta-analysis. The results showed significant effect sizes for specific brain potentials during sexual stimulation (P3: Cohen's d = 1.82, N = 300, LPP: Cohen's d = 2.30, N = 510) with high heterogeneity between the combined studies. Taken together, our review shows how neuroelectric methods can consistently differentiate sexual arousal from other emotional states.
许多关于人类性唤起的综述都集中在不同的脑成像方法和行为观察上。尽管大脑中的神经递质传递主要通过电化学信号进行，但目前还没有关于性唤起的电生理学相关性的系统综述。我们对此主题进行了系统搜索，并综述了包括各种电生理方法在内的 255 项研究。我们的研究结果展示了神经电信号如何用于研究性唤起期间的生殖器体觉定位以及基本的生殖器生理学，以及如何在性高潮期间记录皮质电信号。此外，还分析了健康受试者和性偏好异常者的认知与性唤起相互作用的实验，以及与神经系统疾病相关的性障碍的病例研究。此外，有 25 项专注于认知与性唤起相互作用期间脑电位的研究符合荟萃分析的条件。结果表明，在性刺激期间特定脑电位的效应量显著（P3：Cohen's d=1.82，N=300，LPP：Cohen's d=2.30，N=510），合并研究之间存在高度异质性。总的来说，我们的综述表明，神经电方法如何能够将性唤起与其他情绪状态区分开来。
