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High-resolution cross-reactive array for alkaloids.

作者信息

Pei Renjun, Shen Aihua, Olah Mark J, Stefanovic Darko, Worgall Tilla, Stojanovic Milan N

机构信息

Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, NY 10032, USA.

出版信息

Chem Commun (Camb). 2009 Jun 14(22):3193-5. doi: 10.1039/b900001a. Epub 2009 May 1.

Abstract

A high-resolution cross-reactive array capable of classifying alkaloids over a range of concentrations was generated by systematic introduction of a nitroindole analog into a hydrophobic pocket within a DNA three-way junction to match structural motifs presented by the analytes.

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