Shojania Kaveh G, Jennings Alison, Mayhew Alain, Ramsay Craig R, Eccles Martin P, Grimshaw Jeremy
Director, University of Toronto Centre for Patient Safety, Sunnybrook Health Sciences Centre, Room D474, 2075 Bayview Avenue, Toronto, Ontario, Canada, M4N 3M5.
Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD001096. doi: 10.1002/14651858.CD001096.pub2.
The opportunity to improve care by delivering decision support to clinicians at the point of care represents one of the main incentives for implementing sophisticated clinical information systems. Previous reviews of computer reminder and decision support systems have reported mixed effects, possibly because they did not distinguish point of care computer reminders from e-mail alerts, computer-generated paper reminders, and other modes of delivering 'computer reminders'.
To evaluate the effects on processes and outcomes of care attributable to on-screen computer reminders delivered to clinicians at the point of care.
We searched the Cochrane EPOC Group Trials register, MEDLINE, EMBASE and CINAHL and CENTRAL to July 2008, and scanned bibliographies from key articles.
Studies of a reminder delivered via a computer system routinely used by clinicians, with a randomised or quasi-randomised design and reporting at least one outcome involving a clinical endpoint or adherence to a recommended process of care.
Two authors independently screened studies for eligibility and abstracted data. For each study, we calculated the median improvement in adherence to target processes of care and also identified the outcome with the largest such improvement. We then calculated the median absolute improvement in process adherence across all studies using both the median outcome from each study and the best outcome.
Twenty-eight studies (reporting a total of thirty-two comparisons) were included. Computer reminders achieved a median improvement in process adherence of 4.2% (interquartile range (IQR): 0.8% to 18.8%) across all reported process outcomes, 3.3% (IQR: 0.5% to 10.6%) for medication ordering, 3.8% (IQR: 0.5% to 6.6%) for vaccinations, and 3.8% (IQR: 0.4% to 16.3%) for test ordering. In a sensitivity analysis using the best outcome from each study, the median improvement was 5.6% (IQR: 2.0% to 19.2%) across all process measures and 6.2% (IQR: 3.0% to 28.0%) across measures of medication ordering. In the eight comparisons that reported dichotomous clinical endpoints, intervention patients experienced a median absolute improvement of 2.5% (IQR: 1.3% to 4.2%). Blood pressure was the most commonly reported clinical endpoint, with intervention patients experiencing a median reduction in their systolic blood pressure of 1.0 mmHg (IQR: 2.3 mmHg reduction to 2.0 mmHg increase).
AUTHORS' CONCLUSIONS: Point of care computer reminders generally achieve small to modest improvements in provider behaviour. A minority of interventions showed larger effects, but no specific reminder or contextual features were significantly associated with effect magnitude. Further research must identify design features and contextual factors consistently associated with larger improvements in provider behaviour if computer reminders are to succeed on more than a trial and error basis.
通过在医疗服务点为临床医生提供决策支持来改善医疗服务的机会,是实施复杂临床信息系统的主要动机之一。先前对计算机提醒和决策支持系统的综述报告了不同的效果,这可能是因为它们没有区分医疗服务点的计算机提醒与电子邮件提醒、计算机生成的纸质提醒以及其他提供“计算机提醒”的方式。
评估在医疗服务点向临床医生提供的屏幕式计算机提醒对医疗服务过程和结果的影响。
我们检索了截至2008年7月的Cochrane EPOC组试验注册库、MEDLINE、EMBASE、CINAHL和CENTRAL,并查阅了关键文章的参考文献。
关于通过临床医生常规使用的计算机系统提供提醒的研究,采用随机或半随机设计,并报告至少一项涉及临床终点或对推荐医疗流程依从性的结果。
两位作者独立筛选研究的合格性并提取数据。对于每项研究,我们计算了对目标医疗流程依从性的中位数改善情况,并确定了改善最大的结果。然后,我们使用每项研究的中位数结果和最佳结果,计算了所有研究中医疗流程依从性的中位数绝对改善情况。
纳入了28项研究(共报告了32项比较)。在所有报告的流程结果中,计算机提醒使流程依从性的中位数提高了4.2%(四分位间距(IQR):0.8%至18.8%),药物订购方面提高了3.3%(IQR:0.5%至10.6%),疫苗接种方面提高了3.8%(IQR:0.5%至6.6%),检查订购方面提高了3.8%(IQR:0.4%至16.3%)。在使用每项研究最佳结果的敏感性分析中,所有流程指标的中位数改善为5.6%(IQR:2.0%至19.2%),药物订购指标的中位数改善为6.2%(IQR:3.0%至28.0%)。在报告二分法临床终点的8项比较中,干预组患者的中位数绝对改善为2.5%(IQR:1.3%至4.2%)。血压是最常报告的临床终点,干预组患者的收缩压中位数降低了1.0 mmHg(IQR:降低2.3 mmHg至升高2.0 mmHg)。
医疗服务点的计算机提醒通常能使提供者行为有小到适度的改善。少数干预措施显示出更大的效果,但没有特定的提醒或背景特征与效果大小有显著关联。如果计算机提醒要在试验和错误之外取得成功,进一步的研究必须确定与提供者行为更大改善始终相关的设计特征和背景因素。