Jegelka Markus, Plietker Bernd
Institut für Organische Chemie, FB Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569 Stuttgart, Germany.
Org Lett. 2009 Aug 6;11(15):3462-5. doi: 10.1021/ol901297s.
In contrast to the formation of C-O and C-N bonds it was only recently that the selective C-S bond formation by means of transition metal complexes moved more into the center of research. This is somewhat surprising given the fact that the sulfur atom in a functional group can possess different oxygenation levels which correspond to different chemical properties and reaction portfolios. Herein we wish to communicate a regioselective Fe-catalyzed allylic sulfonation that allows for the preparation of various chiral aryl allyl sulfones in good to excellent yields.
与碳 - 氧键和碳 - 氮键的形成不同，通过过渡金属配合物进行选择性碳 - 硫键形成直到最近才更多地成为研究的核心。鉴于官能团中的硫原子可以具有不同的氧化态，这些氧化态对应于不同的化学性质和反应组合，这有点令人惊讶。在此，我们希望交流一种区域选择性铁催化的烯丙基磺化反应，该反应能够以良好到优异的产率制备各种手性芳基烯丙基砜。
