Finley Kristen, Giannamore Martin, Bennett Marialice, Hall Laura
Ambulatory Care Pharmacy Practice Resident, College of Pharmacy, Ohio State University, Columbus, OH, USA.
J Am Pharm Assoc (2003). 2009 Jul-Aug;49(4):544-8. doi: 10.1331/JAPhA.2009.08004.
To assess patients' knowledge of gastroesophageal reflux disease (GERD) lifestyle modifications and to identify patients' behaviors associated with GERD management before and after an educational intervention.
The study was conducted at five indigent health centers in Columbus, OH, from January to May 2007. A total of 30 adult patients with GERD receiving proton pump inhibitor (PPI) therapy were assessed. In both the control and intervention groups, a pretest consisting of 23 questions assessed patients' knowledge regarding GERD and lifestyle modifications. A presurvey consisting of eight questions assessed patients' current behaviors associated with GERD management using both lifestyle modifications and PPIs. The intervention group also received approximately 10 minutes of education on lifestyle modifications. A posttest and postsurvey were given 8 to 12 weeks after the initial session to both groups. Main outcome measures included change in test score for patients in the control versus intervention groups. Outcomes measured on the pre- and postsurvey included source of heartburn information/education, smoking status, trigger foods eaten weekly, frequency of monthly heartburn episodes, and PPI adherence.
The average change in test scores was 1.33 and 2.73 in the control and intervention groups, respectively (P = 0.11; two-sample t test). The frequency of monthly heartburn episodes increased postsurvey in the control group; however, the frequency of monthly episodes decreased in the intervention group. For the presurvey, no patients reported ever having received GERD education from a pharmacist. For the postsurvey, all 15 patients in the intervention group stated that they had received education from a pharmacist.
The intervention group patients had higher mean change in test scores compared with the control group, although this difference did not reach statistical significance. The failure to achieve statistical significance may have resulted from the small sample size. The pharmacist-patient interaction improved patient knowledge and some behaviors made in GERD management and symptom reduction.
评估患者对胃食管反流病(GERD)生活方式调整的了解程度,并确定在教育干预前后与GERD管理相关的患者行为。
该研究于2007年1月至5月在俄亥俄州哥伦布市的五个贫困医疗中心进行。共评估了30名接受质子泵抑制剂(PPI)治疗的成年GERD患者。在对照组和干预组中,一个由23个问题组成的预测试评估了患者对GERD和生活方式调整的了解。一个由8个问题组成的预调查评估了患者目前使用生活方式调整和PPI进行GERD管理的行为。干预组还接受了约10分钟的生活方式调整教育。在初次 session 后8至12周,对两组进行了后测试和后调查。主要结局指标包括对照组与干预组患者测试分数的变化。在预调查和后调查中测量的结局包括烧心信息/教育来源、吸烟状况、每周食用的触发食物、每月烧心发作频率以及PPI依从性。
对照组和干预组测试分数的平均变化分别为1.33和2.73(P = 0.11;两样本t检验)。对照组后调查中每月烧心发作频率增加;然而,干预组中每月发作频率降低。对于预调查,没有患者报告曾从药剂师那里接受过GERD教育。对于后调查,干预组的所有15名患者表示他们从药剂师那里接受了教育。
与对照组相比,干预组患者测试分数的平均变化更高,尽管这种差异未达到统计学意义。未达到统计学意义可能是由于样本量小。药剂师与患者的互动改善了患者的知识以及在GERD管理和症状减轻方面的一些行为。