Brandsborg Birgitte, Dueholm Margit, Nikolajsen Lone, Kehlet Henrik, Jensen Troels S
Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark.
Clin J Pain. 2009 May;25(4):263-8. doi: 10.1097/AJP.0b013e31819655ca.
Chronic pain after hysterectomy is reported by 5% to 32% of women, but it is unknown whether the pain is a result of surgery or can be attributable to other factors such as preoperative and postoperative pain, physical, and psychosocial status. The aim of this prospective study was therefore to study the role of surgery and other possible predictors for pain 4 months after hysterectomy.
Ninety women referred for hysterectomy for benign conditions completed the study. The women were interviewed and completed pain questionnaires before surgery and after 3 weeks and 4 months. Questions were about pain location, intensity, and frequency, as well as medical treatment and impact on daily living. In addition, the Short Form-36 General Health Status Questionnaire and Coping Strategies Questionnaire were completed before surgery.
Fifteen women (16.7%) had persistent pain 4 months after hysterectomy. In 11 women, the pain resembled their preoperative pain, whereas 4 women had pain likely to be related to surgery. Preoperative "pain problems elsewhere" and a high "acute postoperative pain intensity" were associated with having pain 4 months after hysterectomy (P = 0.004 and P = 0.034). A similar tendency was seen for preoperative "pelvic pain" (P = 0.059). Women with pain at 4 months reported lower quality of life in 4 Short Form-36 subscales and less control of pain preoperatively (P < 0.05 and P = 0.023).
Pain persisting 4 months after hysterectomy is most often related to preoperative factors and acute postoperative pain. The relative contribution of surgery itself is small.
据报道,5%至32%的女性在子宫切除术后会出现慢性疼痛,但尚不清楚这种疼痛是手术所致,还是可归因于其他因素,如术前和术后疼痛、身体及心理社会状况。因此,这项前瞻性研究的目的是探讨手术及其他可能的预测因素在子宫切除术后4个月疼痛中的作用。
90名因良性疾病接受子宫切除术的女性完成了该研究。这些女性在手术前、术后3周和4个月接受了访谈并填写了疼痛问卷。问题涉及疼痛部位、强度、频率,以及医疗治疗和对日常生活的影响。此外,在手术前还填写了简短健康调查问卷-36和应对策略问卷。
15名女性(16.7%)在子宫切除术后4个月仍有持续性疼痛。11名女性的疼痛与术前疼痛相似,而4名女性的疼痛可能与手术有关。术前“其他部位疼痛问题”和较高的“术后急性疼痛强度”与子宫切除术后4个月疼痛相关(P = 0.004和P = 0.034)。术前“盆腔疼痛”也有类似趋势(P = 0.059)。术后4个月仍疼痛的女性在简短健康调查问卷-36的4个分量表中生活质量较低,且术前对疼痛的控制较差(P < 0.05和P = 0.023)。
子宫切除术后持续4个月的疼痛最常与术前因素和术后急性疼痛有关。手术本身的相对作用较小。