Mair T S, Hillyer M H, Taylor F G, Pearson G R
Department of Veterinary Medicine, University of Bristol, School of Veterinary Science, Langford, Avon, UK.
Equine Vet J. 1991 Sep;23(5):344-6. doi: 10.1111/j.2042-3306.1991.tb03735.x.
Specificity of the oral glucose tolerance test (OGTT) for the diagnosis of small intestinal malabsorption in the horse was assessed by comparing the results of OGTT with the results of a histopathological examination of the small intestine in 42 adult horses affected by chronic weight loss. The horses were assigned to three groups on the basis of the results of the test. Five horses were considered to have a normal OGTT absorption result (Group 1); all the horses had a histologically normal small intestine. Twenty-five horses had a partial malabsorption result (Group 2) seven of which had normal small intestinal morphology, whereas the remaining 18 had a variety of pathological lesions including lymphosarcoma, villous atrophy, granulomatous enteritis and eosinophilic gastroenteritis. Twelve of the 42 horses had a total malabsorption result (Group 3), and all had a severe infiltrative lesion in the small intestinal wall (either lymphosarcoma or granulomatous enteritis).
通过比较42匹受慢性体重减轻影响的成年马的口服葡萄糖耐量试验（OGTT）结果与小肠组织病理学检查结果，评估了OGTT对马小肠吸收不良诊断的特异性。根据试验结果，将这些马分为三组。五匹马被认为OGTT吸收结果正常（第1组）；所有马的小肠组织学均正常。25匹马有部分吸收不良结果（第2组），其中7匹小肠形态正常，而其余18匹有各种病理病变，包括淋巴肉瘤、绒毛萎缩、肉芽肿性肠炎和嗜酸性胃肠炎。42匹马中有12匹有完全吸收不良结果（第3组），且所有马的小肠壁均有严重浸润性病变（淋巴肉瘤或肉芽肿性肠炎）。
