Evrard J, Khamis J, Rausin L, Legat C, Bertrand J M, Battisti O, Langhendries J P
University of Liège, Department of Paediatrics, Montegnée-Rocourt, Belgium.
Eur J Pediatr. 1991 Sep;150(11):757-60. doi: 10.1007/BF02026705.
Of 46 infants with a diagnosis of necrotizing enterocolitis (NEC) admitted to the neonatal intensive care unit over the period 1981-1985, 40 have been followed from 2 to 6 years after the acute episode. A contrast enema (CE) to look for intestinal strictures (IS) was performed either during the first months in surgically managed patients, or between 2 and 6 years in asymptomatic patients. Clinical, laboratory and radiology parameters collected during the 7 days following NEC were used to establish a score which was correlated with radiological data obtained after CE. Of the 40 infants, 17 developed symptomatic or asymptomatic IS and 16 of these 17 infants has a score greater than or equal to 7. Nineteen of the 23 patients without IS had a score less than 7. We conclude that the proposed score established on day 8 after onset of NEC helps to identify infants at higher risk of developing IS and for whom closer follow up appears necessary.
在1981年至1985年期间入住新生儿重症监护病房的46例诊断为坏死性小肠结肠炎（NEC）的婴儿中，40例在急性发作后2至6年进行了随访。对于接受手术治疗的患者，在最初几个月内进行了对比灌肠（CE）以寻找肠道狭窄（IS）；对于无症状患者，则在2至6岁之间进行。在NEC发生后的7天内收集的临床、实验室和放射学参数用于建立一个评分，该评分与CE后获得的放射学数据相关。在这40例婴儿中，17例出现了有症状或无症状的IS，这17例婴儿中有16例的评分大于或等于7。23例没有IS的患者中有19例的评分低于7。我们得出结论，在NEC发病后第8天建立的拟议评分有助于识别发生IS风险较高的婴儿，对于这些婴儿似乎有必要进行更密切的随访。
