Division of Gerontology Research, National Health Research Institutes, Miaoli County, Taiwan.
Osteoporos Int. 2010 May;21(5):773-84. doi: 10.1007/s00198-009-1013-z. Epub 2009 Jul 14.
We conducted a matched case-control study of hip fracture in older adults. Our findings suggest that hip fracture risk was determined by multiple factors. Older women characterized by low consumption of milk, peak flow rate, grip strength, and bone mineral density (BMD) had increased risk of hip fracture. Older men with impaired cognitive function and low BMD were also at higher risk of hip fracture.
Multiple factors contribute to low-trauma hip fracture in older adults. The aim of this study was to determine important characteristics of hip fracture in older population.
A total of 228 patients with first low-trauma hip fracture were matched with 497 controls. All 77 potential risk factors of hip fracture organized into 13 groups were analyzed using conditional logistic regression.
Low milk intake, peak flow rate, hand grip strength, and bone mineral density in women and low mini-mental state examination score and bone mineral density in men were further identified to be independently associated with elevated hip fracture risk.
The factors found in our study may help understand the etiology of hip fracture and be further adopted to evaluate the risk of hip fracture in community and clinical setting.
我们进行了一项老年人髋部骨折的配对病例对照研究。我们的研究结果表明，髋部骨折的风险是由多种因素决定的。牛奶摄入量低、峰值流速、握力和骨密度（BMD）低的老年女性髋部骨折风险增加。认知功能受损和 BMD 低的老年男性髋部骨折风险也较高。
多种因素导致老年人低创伤性髋部骨折。本研究旨在确定老年人群髋部骨折的重要特征。
共纳入 228 例首次低创伤性髋部骨折患者，与 497 例对照进行匹配。使用条件逻辑回归分析了所有 77 个潜在的髋部骨折危险因素，分为 13 组。
女性牛奶摄入量低、峰值流速、手握力和骨密度，以及男性简易精神状态检查评分和骨密度低与髋部骨折风险升高独立相关。
我们研究中发现的因素有助于了解髋部骨折的病因，并进一步用于评估社区和临床环境中的髋部骨折风险。
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