Department of Obstetrics and Gynecology, Osteoporosis Prevention and Treatment Center, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Department of General Surgery, Osteoporosis Prevention and Treatment Center, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan; Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Biomed J. 2018 Oct;41(5):314-320. doi: 10.1016/j.bj.2018.08.001. Epub 2018 Nov 3.
The present study aimed to assess the changes in trend of osteoporosis among the Taiwanese population from 2001 to 2011.
The National Health Insurance Research Database (NHIRD) of Taiwan, containing records from approximately 23 million insures from 2001 to 2011, was analyzed. Insurees aged≧50 years with osteoporosis were identified either from previously documented osteoporotic diagnosis or osteoporosis-related fractures according to Clinical Modification (ICD-9-CM) diagnostic code.
The prevalence of osteoporosis increased from 17.4% in 2001 to 25.0% in 2011. The prevalence trend increased from 2001 to 2005 and plateaued thereafter. During 2001-2005, the incidence rate of hip fracture held steady from 277 to 281 per 100,000 person-years, and decreased thereafter from 262 to 247 per 100,000 person-years. The overall incidence of osteoporosis declined among patients younger than 84 years from 2001 to 2011, especially after 2005. As compared with 2005 and before, the incidence rate of osteoporosis was significantly decreased since 2006.
The secular changes of osteoporosis in Taiwan are quite similar to the trend in western countries. It reveals how osteoporosis awareness and policy interventions can affect the prevalence trend of osteoporosis.
本研究旨在评估 2001 年至 2011 年台湾地区骨质疏松症的趋势变化。
分析了台湾全民健康保险研究数据库（NHIRD）中 2001 年至 2011 年约 2300 万被保险人的记录。50 岁以上被保险人根据临床修正（ICD-9-CM）诊断代码，从之前记录的骨质疏松症诊断或骨质疏松症相关骨折中确定为骨质疏松症。
骨质疏松症的患病率从 2001 年的 17.4%上升到 2011 年的 25.0%。患病率趋势从 2001 年到 2005 年上升，此后趋于平稳。在 2001-2005 年期间，髋部骨折的发病率保持在每 10 万人年 277-281 例，此后从每 10 万人年 262-247 例下降。2001 年至 2011 年，84 岁以下患者的骨质疏松症总发病率下降，尤其是 2005 年以后。与 2005 年及以前相比，自 2006 年以来，骨质疏松症的发病率明显下降。
台湾骨质疏松症的长期变化与西方国家的趋势非常相似，这揭示了骨质疏松症意识和政策干预如何影响骨质疏松症的流行趋势。
