Kumar B, Sharma V K, Bakaya V, Ayyagari A
Department of Dermatology, Postgraduate Institute of Medical Education & Research, Chandigarh.
Indian J Med Res. 1991 Jul;93:236-9.
Microbial flora especially anaerobes were studied in 67 patients with genital ulcers due to chancroid (diagnosed clinically) and 53 controls with genital ulcers due to other causes. The aerobic flora was similar in patients of chancroid with or without associated bubo and in controls. Anaerobes were however, isolated with higher frequency from chancroid ulcers associated with fluctuant bubo compared to those without bubo (P less than 0.01) and with non-fluctuant bubo (P less than 0.05). Anaerobic bacteria like Bacteroides melaninogenicus, B. fragilis and anaerobic cocci may play a role in the perpetuation of genital ulcers and development of bubo in chancroid.
对67例临床诊断为软下疳所致生殖器溃疡的患者以及53例其他原因所致生殖器溃疡的对照者的微生物菌群,尤其是厌氧菌进行了研究。有或无相关腹股沟淋巴结炎的软下疳患者的需氧菌菌群与对照者相似。然而,与无腹股沟淋巴结炎的软下疳溃疡相比,从伴有波动感腹股沟淋巴结炎的软下疳溃疡中分离出厌氧菌的频率更高(P<0.01),与无波动感腹股沟淋巴结炎的软下疳溃疡相比也更高(P<0.05)。诸如产黑色素拟杆菌、脆弱拟杆菌和厌氧球菌等厌氧菌可能在软下疳所致生殖器溃疡的持续存在以及腹股沟淋巴结炎的发展中起作用。