Agarwal K N, Agarwal D K, Mishra K P
Department of Paediatrics, Banaras Hindu University, Varanasi.
Indian J Med Res. 1991 Aug;94:277-80.
A total of 418 pregnant women at 16-24 wk of gestation, from six subcentres of a rural block of Varanasi district were selected. Pregnant women (137 of 215) from 3 subcentres received the supplementation of 60 mg elemental iron as ferrous sulphate combined with 500 micrograms folic acid, daily for 100 days (study group) and 123 (of 203) pregnant women from the other 3 subcentres without supplementation (control group) could be evaluated for their pregnancy outcome. The haemoglobin and serum ferritin levels increased significantly in the study group. In the latter, the mean birth weight was 2.88 +/- 0.41 kg with low birth weight incidence of 20.4 per cent as compared to the control figures of 2.59 +/- 0.34 kg and 37.9 per cent respectively. The incidence of low birth weight was further reduced to 12.1 per cent if the supplementation could be started by 16-19 wk of gestation.
从瓦拉纳西地区一个农村街区的六个分中心选取了总共418名妊娠16 - 24周的孕妇。来自3个分中心的孕妇（215名中的137名）每天接受60毫克元素铁（以硫酸亚铁形式）与500微克叶酸的补充剂，持续100天（研究组），来自其他3个分中心的123名（203名中的）未接受补充剂的孕妇（对照组）可对其妊娠结局进行评估。研究组的血红蛋白和血清铁蛋白水平显著升高。在研究组中，平均出生体重为2.88±0.41千克，低出生体重发生率为20.4%，而对照组的相应数据分别为2.59±0.34千克和37.9%。如果在妊娠16 - 19周开始补充剂，低出生体重发生率可进一步降至12.1%。
