Goldstein L J, Rypins E B
Department of Surgery, University of California, Irvine Medical Center, Orange 92668.
Int J Biomed Comput. 1991 Oct;29(1):23-9. doi: 10.1016/0020-7101(91)90010-c.
We developed a computer program for calculating hemodynamic parameters in a segment of vessel or catheter using Poiseuille's Law. The program analyzes flow, pressure, flow velocity, total fluid volume, pulse pressure, resistance and Reynolds number in a segment of vessel. The user can dilate or constrict at any position along its length for modeling stenoses or aneurysms. Viscosity, fluid density, length, and intrinsic radius can be varied to simulate atherosclerotic vessels. Idealized linear hemodynamics of an abdominal aortic aneurysm or a coarcted aorta can be modeled from angiographic data. Interactive results are displayed graphically and can be printed for future reference. The program can estimate catheter, graft or vascular resistances, flow velocity in atherogenic arteries, and the likelihood of achieving laminar flow.
我们开发了一个计算机程序,用于根据泊肃叶定律计算血管段或导管中的血流动力学参数。该程序可分析血管段中的流量、压力、流速、总液体体积、脉压、阻力和雷诺数。用户可以在其长度的任何位置进行扩张或收缩,以模拟狭窄或动脉瘤。可以改变粘度、流体密度、长度和固有半径,以模拟动脉粥样硬化血管。可以根据血管造影数据对腹主动脉瘤或缩窄性主动脉的理想化线性血流动力学进行建模。交互式结果以图形方式显示,并可打印以供将来参考。该程序可以估计导管、移植物或血管阻力、动脉粥样硬化动脉中的流速以及实现层流的可能性。