Klapper J A, Stanton J S
Colorado Neurology and Headache Center, Denver 80218.
Headache. 1991 Sep;31(8):523-4. doi: 10.1111/j.1526-4610.1991.hed3108523.x.
Ketorolac IM was compared to DHE and metoclopramide IV in migraine patients whose regular abortive medication had failed and who presented to a headache clinic for acute treatment. Pain scale ratings and ratings of ability to function were recorded before and after injection. Ketorolac provided moderate relief in headache in six of nine patients compared to eight of nine given DHE and metoclopramide. The average improvement in patients receiving DHE and metoclopramide was greater in pain (p = .031) and disability scores (p = .057), than in those patients given ketorolac.
在常规止痛药物治疗无效且前往头痛门诊接受急性治疗的偏头痛患者中，将酮咯酸肌内注射与二氢麦角胺及甲氧氯普胺静脉注射进行了比较。在注射前后记录疼痛量表评分和功能能力评分。与接受二氢麦角胺及甲氧氯普胺治疗的9名患者中的8名相比，接受酮咯酸治疗的9名患者中有6名头痛得到中度缓解。接受二氢麦角胺及甲氧氯普胺治疗的患者在疼痛（p = 0.031）和残疾评分（p = 0.057）方面的平均改善程度大于接受酮咯酸治疗的患者。
