Droc G, Grigorescu B, Grigoroiu M, Tomulescu V, Tulbure D
Centrul de ATI, Institutul Clinic Fundeni, Bucureşti.
Chirurgia (Bucur). 2009 May-Jun;104(3):259-65.
New surgical techniques cannot be safely and widely performed in human subjects unless they are first applied to large animal models. Experimental model using swine as surgical practice subject is one of the most reliable and widely practiced, taking into consideration the similarity between human and swine anatomy. Based on our large experience (around 100 pigs) we hereby present important aspects of handling and anesthesia procedures for pigs. Our goal is to share our experience with young surgical and anesthesia investigators who are planning investigations using pig as an experimental animal.
除非新的外科技术首先应用于大型动物模型,否则它们无法在人类受试者身上安全且广泛地实施。考虑到人类和猪的解剖结构相似性,以猪作为外科手术实践对象的实验模型是最可靠且应用最广泛的模型之一。基于我们丰富的经验(约100头猪),在此我们介绍猪的处理和麻醉程序的重要方面。我们的目标是与计划使用猪作为实验动物进行研究的年轻外科和麻醉研究人员分享我们的经验。