Department of Integrative Physiology, University of North Texas Health Science Center, Fort Worth, TX, USA.
Lab Anim (NY). 2010 Mar;39(3):80-5. doi: 10.1038/laban0310-80.
Goats are used as animal models for surgery and trauma research. The authors discuss appropriate methods for induction of anesthetics, intubation and surgical maintenance of the goat during acute experimentation. Risks imposed by the Q fever pathogen Coxiella burnetii are described, as well as measures that have proven effective in minimizing zoonotic transmission of this pathogen to laboratory personnel. With appropriate knowledge of its applications, peri- and intra-operative management and limitations, the goat is a suitable animal model for a variety of biomedical research applications.
山羊被用作手术和创伤研究的动物模型。作者讨论了在急性实验中诱导麻醉、插管和维持山羊手术的适当方法。还描述了由 Q 热病原体贝氏柯克斯体带来的风险，以及已被证明可有效降低该病原体向实验室人员发生人畜共患病传播的措施。通过适当了解其应用、围手术期管理和局限性，山羊是各种生物医学研究应用的合适动物模型。
