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[采用单纯低温逆行脑灌注行主动脉弓置换术治疗长时间脑循环停止——1例成功病例报告]

[Aortic arch replacement by simple hypothermic retrograde cerebral perfusion for long cerebral circulatory arrest--a successful case report].

作者信息

Takamoto S, Matsuda T, Harada M, Kouno T, Hojo H

机构信息

Division of Cardiovascular Surgery, Showa General Hospital, Tokyo, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1991 Sep;39(9):1798-802.

PMID:1960463
Abstract

We have recently discovered that hypothermic cerebral retrograde perfusion can be performed by simply elevating the central venous pressure in Trendelenburg's position during aortic arch surgery. During deep hypothermic perfusion of the lower half of the body with an occlusion balloon in the descending aorta, oxygen saturated venous blood supplied the brain with oxygen. A successful case is reported. A case was 53 y.o. woman of dissecting aortic aneurysm DeBakey type II, with a true aortic arch aneurysm. Under median sternotomy the right atrium and the femoral artery were cannulated for cardiopulmonary bypass. With the brain under retrograde perfusion at a rectal temperature of 16 degrees C and a central venous pressure of 10-15 mmHg, the ascending to the descending aorta was replaced. Blood flowed into the aortic arch from the arch vessels was blackish in color. Brain circulatory arrest time was 81 min. Postoperative course was uneventful. It is suggested that this simple retrograde cerebral perfusion during hypothermic aortic arch surgery protected the brain for an extended brain circulatory arrest time, and eliminated the need for clamping at the aortic arch and the arch vessels, and simplified the operative procedure.

摘要

我们最近发现,在主动脉弓手术期间,通过在特伦德伦伯格体位简单地升高中心静脉压即可进行低温脑逆行灌注。在降主动脉中使用阻塞球囊对身体下半部进行深低温灌注时,氧合饱和的静脉血为大脑提供氧气。本文报告了一例成功病例。患者为一名53岁的女性,患有DeBakey II型主动脉夹层动脉瘤,伴有真性主动脉弓动脉瘤。在正中胸骨切开术下,将右心房和股动脉插管用于体外循环。在直肠温度为16℃、中心静脉压为10 - 15 mmHg的情况下对大脑进行逆行灌注,置换升主动脉至降主动脉。从主动脉弓血管流入主动脉弓的血液颜色发黑。脑循环停止时间为81分钟。术后病程平稳。提示在低温主动脉弓手术期间这种简单的逆行脑灌注可在延长的脑循环停止时间内保护大脑,无需夹闭主动脉弓和弓血管,简化了手术操作。

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