Division of Vascular Surgery, Hospital Regional Sul, São Paulo/SP, Brasil.
Clinics (Sao Paulo). 2009;64(7):657-64. doi: 10.1590/S1807-59322009000700009.
To compare common carotid intima-media thickness (IMT) between the two major Brazilian ethnic groups (those of African descent and those of European descent) among individuals with one or more risk factors for atherosclerotic disease.
Two hundred and six patients with one or more risk factors for atherosclerotic disease were evaluated in a cross-sectional study in which their clinical, ethnic and Demographic characteristics were collected. All patients underwent duplex ultrasound examination of their carotid vessels to obtain IMT measurements.
One hundred and fifty-three patients (74.3%) had a carotid IMT greater than 1.0 mm at one or more point of measurement in at least one common carotid artery. There was a significant correlation between older age and mean carotid wall thickness (R=0.479 / P<0.01). Multivariate analysis identified male sex, arterial hypertension and older age as variables associated with increased IMT (P<0.05 for all variables). When IMT was compared between the two ethnic groups in this study, no significant differences were noted. Euro-descendants and Afro-descendants had similar IMT values, even when the groups were stratified by degree of IMT (normal vs. increased) and presence of stroke and/or transient ischemic attack (yes vs. no).
The risk factors associated with increased common carotid artery IMT in Brazilian individuals are similar to those in previously described populations. No differences were observed between the two main Brazilian ethnic groups. Longitudinal studies are required for a better evaluation of the incidence, etiologic factors and evolution of carotid intimomedial thickening in this population.
比较两种主要的巴西族裔（非洲裔和欧洲裔）个体中，一个或多个动脉粥样硬化疾病风险因素患者的颈总动脉内膜-中层厚度（IMT）。
在一项横断面研究中，评估了 206 名患有一个或多个动脉粥样硬化疾病风险因素的患者，收集了他们的临床、种族和人口统计学特征。所有患者均接受颈动脉双功能超声检查，以获得 IMT 测量值。
在至少一条颈总动脉的一个或多个部位，153 名（74.3%）患者的颈动脉 IMT 大于 1.0mm。年龄与颈动脉壁平均厚度之间存在显著相关性（R=0.479 / P<0.01）。多变量分析确定男性、高血压和年龄较大是与 IMT 增加相关的变量（所有变量的 P<0.05）。在本研究中比较两个种族群体的 IMT 时，未观察到显著差异。欧洲裔和非洲裔的 IMT 值相似，即使在按 IMT 程度（正常 vs. 增加）和是否存在中风和/或短暂性脑缺血发作（是 vs. 否）分层的情况下也是如此。
与巴西个体颈总动脉 IMT 增加相关的危险因素与先前描述的人群相似。两个主要的巴西族裔之间没有观察到差异。需要进行纵向研究，以更好地评估该人群颈动脉内膜中层增厚的发生率、病因因素和演变。
