Balamurugan Appathurai, Im Lucy, Reeve Gordon, Mehta Paulette, Bates Joseph H
J Ark Med Soc. 2009 Jun;105(12):283-4, 286.
The incidence of invasive female breast cancer declined 6.7% in the United States from 2002 to 2003 following a nationwide decrease in the use of hormone replacement therapy that began in 2002. We used data from the Arkansas Central Cancer Registry to look for similar changes in the incidence of female breast cancer in Arkansas. There was a 9.3% decline in the incidence of invasive female breast cancer in Arkansas in 2003, and the decline continued through 2005. The decline was significantly higher (p<0.05) among invasive cancers, particularly among women ages 50 and older and for those having an estrogen-receptor positive tumor.
2002年开始全国范围内激素替代疗法使用量下降后，2002年至2003年美国侵袭性女性乳腺癌发病率下降了6.7%。我们利用阿肯色州中央癌症登记处的数据来寻找阿肯色州女性乳腺癌发病率的类似变化。2003年阿肯色州侵袭性女性乳腺癌发病率下降了9.3%，且这种下降持续到2005年。侵袭性癌症中的下降幅度显著更高（p<0.05），尤其是50岁及以上女性以及那些患有雌激素受体阳性肿瘤的女性。
