Landkroon A P, de Weerd S, van Vliet-Lachotzki E, Steegers E A P
Department of Obstetrics and Gynecology, Division of Obstetrics and Prenatal Medicine, Erasmus Medical Center, NL-3000 CA otterdam, The Netherlands.
Public Health Genomics. 2010;13(2):89-94. doi: 10.1159/000228980. Epub 2009 Jul 17.
Validation of a self-administered Internet questionnaire for preconception risk assessment.
Women with an appointment at the outpatient clinics for preconception care or fertility at the Erasmus Medical Center Rotterdam were requested to fill out the online questionnaire prior to attendance. Subsequently, the items of the questionnaire were verified by history taking during the first or next appointment. Agreement between the 2 screening methods (Internet vs. history taking) was calculated using Kappa statistic.
Most lifestyle variables, including smoking, alcohol, and dietary items, showed a good to high level of agreement when compared to the interview. Most medical history and obstetric history items also showed a good to high level of agreement. The use of over-the-counter drugs revealed a poor level of agreement (Kappa = 0.21). The items pertaining to women's family history showed a reasonable level of agreement; however, the partner's family history was unreliable and should be checked at the interview.
The online questionnaire www.zwangerwijzer.nl is a useful tool for the identification of a number of potential risk factors in the preconception care setting and was found to be a an efficient and clear screening instrument by the majority of women. However, additional history taking by trained professionals is necessary to verify several items and to further explore identified risk factors for an adverse pregnancy outcome.
验证一份用于孕前风险评估的自我管理式网络问卷。
要求在鹿特丹伊拉斯姆斯医学中心门诊进行孕前保健或生育咨询的女性在就诊前填写在线问卷。随后，在首次或下次就诊时通过病史采集对问卷项目进行核实。使用Kappa统计量计算两种筛查方法（网络问卷与病史采集）之间的一致性。
与访谈相比，大多数生活方式变量，包括吸烟、饮酒和饮食项目，显示出良好至高程度的一致性。大多数病史和产科病史项目也显示出良好至高程度的一致性。非处方药的使用显示出较低的一致性水平（Kappa = 0.21）。与女性家族史相关的项目显示出合理的一致性水平；然而，伴侣的家族史不可靠，应在访谈时进行核实。
