Shimoide H, Fukui T, Anzai E, Mizutani S
Byotai-Seiri Clinical Laboratory, Tokyo, Japan.
Kekkaku. 1991 Oct;66(10):671-7.
On 397 patients with pulmonary disease due to nontuberculous mycobacteria (NTM) [102 due to M. kansasii (MK) and 295 due to M. avium complex (MAC)] observed at National Tokyo Chest Hospital, 191 patients with pulmonary disease (59 due to MK and 132 due to MAC) observed at Fukujuji Hospital of Antituberculosis Association and 257 patients from whose sputum MK (36) or MAC (221) were isolated in Byotai-Seiri Clinical Laboratory, the distribution of these patients by domicile in Tokyo area was analysed. The percentage of patients with MK disease among the whole patients with MK disease and MAC disease (MK ratio) in each community area was investigated. MK ratio was 30.9% in the 23 wards and 16.4% in Tama section of Tokyo in the patients observed at National Tokyo Chest Hospital. It was 37.0% in the 23 wards and 32.1% in Tama section in the patients observed at Fukujuji Hospital and was 17.7% in the 23 wards and 8.1% in Tama section in the patients observed at Byotai-Seiri Clinical Laboratory. MK ratio in Tokyo was considerably higher in the 23 wards that were densely populated industrial and commercial areas than in Tama section, a comparatively sparsely populated suburb. MK ratio in patients of Ota Hospital located in the 23 wards was higher (36.4%) than that of Tachikawa-Sogo Hospital located in Tama area (10.0%). Regional differences in MK ratio were remarkable in Tokyo area. A high MK ratio appeared to correlate with a high incidence rate of tuberculosis. From the results mentioned above, it was suggested that M.K. disease may be transmitted from person to person.
在东京国立胸部医院观察的397例非结核分枝杆菌（NTM）所致肺部疾病患者中（102例由堪萨斯分枝杆菌[MK]引起，295例由鸟分枝杆菌复合群[MAC]引起），分析了福住寺抗结核协会医院观察的191例肺部疾病患者（59例由MK引起，132例由MAC引起）以及在病院精里临床检验所痰液中分离出MK（36例）或MAC（221例）的257例患者在东京地区的居住地分布情况。调查了各社区区域中MK疾病患者在全部MK疾病和MAC疾病患者中的百分比（MK比率）。在东京国立胸部医院观察的患者中，东京23个区的MK比率为30.9%，多摩地区为16.4%。在福住寺医院观察的患者中，23个区为37.0%，多摩地区为32.1%；在病院精里临床检验所观察的患者中，23个区为17.7%，多摩地区为8.1%。东京23个区作为工商业密集的人口密集区，其MK比率明显高于人口相对稀少的郊区多摩地区。位于23个区的大田医院患者的MK比率（36.4%）高于位于多摩地区的立川综合医院（10.0%）。东京地区MK比率的区域差异显著。高MK比率似乎与高结核病发病率相关。根据上述结果，提示堪萨斯分枝杆菌疾病可能通过人传人传播。
