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喉接触式内镜检查作为前外侧喉切除术手术切缘的辅助方法。

Contact endoscopy of the larynx as an auxiliary method to the surgical margins in frontolateral laryngectomy.

作者信息

Dedivitis R A, Pfuetzenreiter E G, Guimarães A V

机构信息

Postgraduation Course on Health Sciences, Hospital Heliópolis, São Paulo, Brazil.

出版信息

Acta Otorhinolaryngol Ital. 2009 Feb;29(1):16-20.

Abstract

Contact laryngomicroscopy is in vivo laryngeal mucosa microscopic examination and rigid telescopy is a non-invasive technique that enables the systematic observation of many details in the large area of vocal fold mucosa. These are performed during laryngomicroscopy. This study was performed in order to evaluate the use of rigid and contact endoscopy effectiveness in establishing the margins in patients undergoing frontolateral laryngectomy. Ten patients with glottic squamous cell carcinoma underwent frontolateral laryngectomy from 2000 to 2003. Eight were staged as T1bN0M0, whereas two were staged as T2N0M0. During the frontolateral approach, the lesion and its limits were carefully defined, the surgical margins were established under the rigid telescope and the patients' margins were studied under contact endoscopy after methylene blue staining. Frozen section examination of the margins was performed and the histopathological analysis was compared to the surgical and endocopic findings. The infraglottic region and the surgical margins were free of disease in all cases and there was a 100% correlation with the histopathological examination. All patients are alive with no evidence of disease after a minimum of 5 years' follow-up. In conclusion, rigid and contact laryngoscopy is effective in establishing the disease-free surgical margins in patients submitted to frontolateral laryngectomy.

摘要

接触式喉镜检查是对喉黏膜进行的活体显微镜检查,而硬性望远镜式检查是一种非侵入性技术,能够系统地观察声带黏膜大面积区域的许多细节。这些操作在喉镜检查期间进行。本研究旨在评估硬性内镜和接触式内镜在确定接受前外侧喉切除术患者的手术切缘方面的有效性。2000年至2003年,10例声门型鳞状细胞癌患者接受了前外侧喉切除术。8例为T1bN0M0期,2例为T2N0M0期。在前外侧入路过程中,仔细界定病变及其边界,在硬性望远镜下确定手术切缘,并在亚甲蓝染色后通过接触式内镜检查患者的切缘。对切缘进行冰冻切片检查,并将组织病理学分析结果与手术和内镜检查结果进行比较。所有病例的声门下区域和手术切缘均无病变,且与组织病理学检查结果的相关性为100%。所有患者在至少5年的随访后均存活,无疾病证据。总之,硬性喉镜和接触式喉镜在确定接受前外侧喉切除术患者的无病手术切缘方面是有效的。

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