Dedivitis Rogério A, Guimarães André V, Guirado Christiano R
Departments of Head and Neck Surgery, Hospital Ana Costa and Irmandade da Santa Casa da Misericórdia de Santos, Santos, Brazil.
Int Surg. 2005 Apr-Jun;90(2):113-8.
The purpose of this study was to determine the recurrence rate and the long-term survival of patients treated with frontolateral laryngectomy for early glottic cancer. The study is a retrospective analysis of a cohort of patients who underwent frontolateral laryngectomy from 1995 to 2002 with a median follow-up of 48 months. This was a consecutive series of 30 patients with T1bN0 and T2N0 vocal fold carcinoma. Previously treated patients were excluded. Surgical treatment consisted of frontolateral partial vertical laryngectomy and reconstruction with bipedicle sternohyoid muscle flap. Twenty-five patients have been alive with no evidence of the disease. The median follow-up was 48 months (range, 6-85 months). Five patients experienced local recurrence. One of them underwent salvage partial hemilaryngectomy, and 4 underwent wide-field total laryngectomy with adjuvant postoperative radiation therapy. Four of five patients with retreatment were ultimately salvaged, with a median follow-up of 30 months. We had one death caused by the disease. Frontolateral laryngectomy is an efficient treatment for selected cases of early glottic carcinoma.
本研究的目的是确定接受前外侧喉切除术治疗的早期声门癌患者的复发率和长期生存率。该研究是对1995年至2002年接受前外侧喉切除术的一组患者进行的回顾性分析，中位随访时间为48个月。这是连续的30例T1bN0和T2N0声带癌患者。既往接受过治疗的患者被排除在外。手术治疗包括前外侧部分垂直喉切除术和带蒂胸骨舌骨肌瓣重建术。25例患者存活且无疾病证据。中位随访时间为48个月（范围6 - 85个月）。5例患者出现局部复发。其中1例接受挽救性部分半喉切除术，4例接受广泛全喉切除术并术后辅助放疗。5例再次治疗的患者中有4例最终获救，中位随访时间为30个月。我们有1例患者死于该疾病。前外侧喉切除术是治疗部分早期声门癌病例的有效方法。
