Yang Bin, Chen Wen-Hui, Li Qiao-Yun, Xiang Jing-Jing, Xu Ru-Jun
Department of Radiology, Hangzhou First People's Hospital, Hangzhou 310006, Zhejiang Province, China.
World J Gastroenterol. 2009 Jul 21;15(27):3417-20. doi: 10.3748/wjg.15.3417.
To study the dynamic computed tomography (CT) features of hepatic angiomyolipoma (AML) in patients with or without tuberous sclerosis complex (TSC).
The clinical information, CT findings and histopathological results of hepatic AML were analyzed retrospectively in 10 patients.
Hepatic AML was prone to occur in female patients (7/10), and most of the patients (8/10) had no specific symptoms. All tumors presented as well-defined, unenveloped nodules in the liver. Six patients with sporadic hepatic AML had a solitary hepatic nodule with a definite fat component. Non-fat components of the hepatic lesions were enhanced earlier and persistently. Prominent central vessels were noted in the portal venous phase in three patients. In four patients with hepatic AML and TSC, most of the nodules were within the peripheral liver. Seven fat-deficient nodules were found with earlier contrast enhancement and rapid contrast material washout in two patients. Lymphangioleiomyomatosis was found in one patient.
Imaging features of hepatic AML are characteristic. Correct diagnosis preoperatively can be made in combination with clinical features.
研究伴或不伴结节性硬化症(TSC)患者肝血管平滑肌脂肪瘤(AML)的动态计算机断层扫描(CT)特征。
回顾性分析10例肝AML患者的临床资料、CT表现及组织病理学结果。
肝AML多见于女性患者(7/10),多数患者(8/10)无特异性症状。所有肿瘤在肝脏内均表现为边界清晰、无包膜的结节。6例散发性肝AML患者有单个肝结节,且有明确的脂肪成分。肝脏病变的非脂肪成分早期强化且持续强化。3例患者在门静脉期可见明显的中央血管。4例合并TSC的肝AML患者,多数结节位于肝周边。2例患者发现7个脂肪缺乏结节,早期强化且对比剂快速廓清。1例患者发现淋巴管平滑肌瘤病。
肝AML的影像学特征具有特异性。结合临床特征可在术前作出正确诊断。