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结节性硬化症患者的胰腺无功能胰岛细胞瘤：一例报告并文献复习

Nonfunctional islet cell tumor of the pancreas in a patient with tuberous sclerosis: a case report with literature review.

作者信息

Cansu Aysegul, Ahmetoglu Ali, Kul Sibel, Uzman Dilek, Ersoz Safak

机构信息

Department of Radiology, Karadeniz Technical University School of Medicine, Farabi Hospital, Trabzon, Turkey.

Department of Pathology, Karadeniz Technical University School of Medicine, Farabi Hospital, Trabzon, Turkey.

出版信息

J Clin Imaging Sci. 2014 Jan 30;4:3. doi: 10.4103/2156-7514.126022. eCollection 2014.

DOI:10.4103/2156-7514.126022
PMID:24678435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3952375/
Abstract

Islet cell tumors (ICTs) are rare tumors of the pancreas. Association of this type of tumor with tuberous sclerosis is extremely rare. Only 13 cases of pancreatic ICT with tuberous sclerosis have so far been documented in the literature. However, awareness of the association of tuberous sclerosis and ICT is important for early diagnosis and appropriate treatment of this condition. This article presents the case of a 63-year-old female with angiomyolipoma (AML) of the kidney and liver, calcified subependymal nodules and a large mass in the pancreas, which was proven to be an ICT on histopathological examination.

摘要

胰岛细胞瘤（ICTs）是胰腺的罕见肿瘤。这类肿瘤与结节性硬化症的关联极为罕见。迄今为止，文献中仅记载了13例胰腺ICT合并结节性硬化症的病例。然而，了解结节性硬化症与ICT的关联对于该疾病的早期诊断和恰当治疗至关重要。本文介绍了一名63岁女性的病例，该患者患有肾和肝的血管平滑肌脂肪瘤（AML）、钙化的室管膜下结节以及胰腺内的一个大肿块，经组织病理学检查证实为ICT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/5b42e85664ff/JCIS-4-3-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/4db29056bfec/JCIS-4-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/004d29a8a5dc/JCIS-4-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/81f49b35fcb1/JCIS-4-3-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/f788c7a1dc1d/JCIS-4-3-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/5b42e85664ff/JCIS-4-3-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/4db29056bfec/JCIS-4-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/004d29a8a5dc/JCIS-4-3-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/81f49b35fcb1/JCIS-4-3-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/f788c7a1dc1d/JCIS-4-3-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e292/3952375/5b42e85664ff/JCIS-4-3-g006.jpg

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本文引用的文献

1
Pancreatic imaging mimics: part 2, pancreatic neuroendocrine tumors and their mimics.胰腺影像表现类似物：第 2 部分，胰腺神经内分泌肿瘤及其类似物。
AJR Am J Roentgenol. 2012 Aug;199(2):309-18. doi: 10.2214/AJR.12.8627.
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Well-differentiated pancreatic neuroendocrine carcinoma in tuberous sclerosis--case report and review of the literature.结节性硬化症相关高分化胰腺神经内分泌癌——病例报告及文献复习。
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Neuroendocrine tumor of the pancreas in a patient with tuberous sclerosis: a case report and review of the literature.
结节性硬化症患者的胰腺神经内分泌肿瘤：一例报告并文献复习
Int J Surg Pathol. 2012 Aug;20(4):390-5. doi: 10.1177/1066896911428735. Epub 2011 Dec 14.
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Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation.肝血管平滑肌脂肪瘤：动态计算机断层扫描特征与临床相关性
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