Engelsman M, Lu H M, Herrup D, Bussiere M, Kooy H M
Department of Radiation Oncology, Francis H. Burr Proton Therapy Center Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Med Phys. 2009 Jun;36(6):2172-80. doi: 10.1118/1.3121489.
Proton radiotherapy centers that currently use passively scattered proton beams do field specific calibrations for a non-negligible fraction of treatment fields, which is time and resource consuming. Our improved understanding of the passive scattering mode of the IBA universal nozzle, especially of the current modulation function, allowed us to re-commission our treatment control system for accurate delivery of SOBPs of any range and modulation, and to predict the output for each of these fields. We moved away from individual field calibrations to a state where continued quality assurance of SOBP field delivery is ensured by limited system-wide measurements that only require one hour per week. This manuscript reports on a protocol for generation of desired SOBPs and prediction of dose output.
目前使用被动散射质子束的质子放射治疗中心，会针对相当一部分治疗野进行特定野的校准，这既耗时又耗资源。我们对IBA通用喷嘴的被动散射模式，尤其是电流调制功能有了更深入的了解，这使我们能够重新调试治疗控制系统，以精确输送任何射程和调制的扩展野布拉格峰（SOBP），并预测每个野的输出剂量。我们不再进行单个野的校准，而是进入了一种状态，即通过每周仅需一小时的有限全系统测量来确保SOBP野输送的持续质量保证。本手稿报告了一种生成所需SOBP和预测剂量输出的方案。
