Bauer K, Götz M, Roithmaier A, Prölss A, Bovermann G, Versmold H
Neonatologie, Frauenklinik Grosshadern, Ludwig-Maximilians-Universität, München.
Monatsschr Kinderheilkd. 1991 Aug;139(8):452-6.
In 9 ventilated preterm infants (birth weight 810-1310 g, gestational age 26-30 weeks) we measured total body water (D2O dilution), extracellular volume (sucrose dilution) and renal function parameters at birth and when postnatal weight loss exceeded 5% of birth weight together with day to day changes of weight, fluid balance, and serum electrolytes. A significant postnatal weight loss (-89 +/- 47 g) occurred together with a reduction of total body water (-102 +/- 95 ml) and extracellular volume (-98 +/- 59 ml) in the first three days of life. The intracellular volume did not change. At the same time fluid balance was negative due to a high extrarenal water loss on day 1 and an increasing diuresis on the following days. The serum sodium concentration remained unchanged during postnatal water loss, because the negative fluid balance was accompanied by a negative sodium balance.
在9名机械通气的早产儿（出生体重810 - 1310克，胎龄26 - 30周）中，我们在出生时以及出生后体重减轻超过出生体重的5%时，测量了全身水含量（重水稀释法）、细胞外液量（蔗糖稀释法）和肾功能参数，同时还测量了每日体重、液体平衡和血清电解质的变化。出生后前三天出现了显著的体重减轻（-89±47克），同时全身水含量减少（-102±95毫升），细胞外液量减少（-98±59毫升）。细胞内液量未发生变化。与此同时，由于出生后第1天肾外失水量高以及随后几天尿量增加，液体平衡呈负值。出生后体重减轻期间血清钠浓度保持不变，因为负液体平衡伴随着负钠平衡。
