Pauls J, Bauer K, Versmold H
Department of Paediatrics, Freie Universität Berlin, Universitätsklinikum Benjamin Franklin, Germany.
Eur J Pediatr. 1998 May;157(5):416-21. doi: 10.1007/s004310050842.
No body weight curves are available for preterm infants < 1000 g birth weight receiving early enteral and parenteral nutrition. Postnatal weight changes of 136 infants with a birth weight < 1000 g were analysed retrospectively. Body weight curves for the first 30 days of life were generated for five separate birth weight groups (430-599 g, 600-699 g, 700-799 g, 800-899 g, 900-999 g). All infants had received intravenous glucose and amino acids from day 1 and intravenous lipids from day 2. Enteral feeding was started on day 1. Thus caloric intake (+/-SD) was advanced to 384+/-46 kJ/kg per day (92+/-11 kcal/kg/day) in the 1st week of life. In 136 preterm infants mean postnatal weight loss was 10.1%+/-4.6% of birth weight, birth weight was regained at a mean postnatal age of 11+/-3.7 days, but significantly earlier (7.8+/-3.5 days) in the lowest compared to the highest weight group. Mean subsequent weight gain was 15.7+/-7.2 g/ kg per day. This was accomplished by exclusive enteral nutrition from day 20 (median).
Our body weight curves are more adequate to evaluate growth of preterm infants than older published reference values because they are based on infants treated according to current nutritional standards.
目前尚无出生体重小于1000克的早产儿接受早期肠内和肠外营养时的体重曲线。对136例出生体重小于1000克的婴儿的出生后体重变化进行了回顾性分析。为五个不同的出生体重组（430 - 599克、600 - 699克、700 - 799克、800 - 899克、900 - 999克）生成了出生后前30天的体重曲线。所有婴儿从第1天开始接受静脉输注葡萄糖和氨基酸，从第2天开始接受静脉输注脂肪乳剂。第1天开始肠内喂养。因此，在出生后第1周，热量摄入（±标准差）增加到384±46千焦/千克/天（92±11千卡/千克/天）。136例早产儿出生后平均体重下降为出生体重的10.1%±4.6%，出生体重在出生后平均11±3.7天恢复，但体重最低组相比最高组明显更早（7.8±3.5天）恢复。随后平均体重增加为15.7±7.2克/千克/天。这是通过从第20天（中位数）开始完全肠内营养实现的。
我们的体重曲线比以往公布的参考值更适合评估早产儿的生长情况，因为它们基于按照当前营养标准治疗的婴儿。
