Department of Obstetrics and Gynaecology, University College London, London, UK.
BJOG. 2009 Oct;116(11):1515-9. doi: 10.1111/j.1471-0528.2009.02293.x. Epub 2009 Jul 22.
Saliva progesterone and oestriol concentrations were determined weekly from 24 weeks of gestation in women at increased risk of preterm delivery. Samples were analysed from 28 women with spontaneous onset of labour and delivery before 37 weeks of gestation, and 64 who delivered at term. Saliva progesterone was lower in the 12 women delivering before 34 weeks than in those delivering later, between 34 and 37 weeks (P = 0.007) or at term (P = 0.009). Measurement of saliva progesterone may be of value in the prediction of early preterm labour and in determining which women might benefit from progesterone supplementation.
从 24 周妊娠开始，每周检测高危早产孕妇的唾液孕酮和雌三醇浓度。分析了 28 名自发早产（妊娠 37 周前）和 64 名足月产孕妇的样本。12 名 34 周前分娩的孕妇唾液孕酮水平低于 34-37 周分娩者（P=0.007）和足月产者（P=0.009）。唾液孕酮检测可能有助于预测早产，并确定哪些孕妇可能从孕激素补充中受益。
