Hailes J, Burger H
Med J Aust. 1977 May 28;1(22):803-6. doi: 10.5694/j.1326-5377.1977.tb131138.x.
The majority of women experience a variety of symptoms at the time of the menopause, but these are frequently regarded as being unworthy of management by their doctors. Recent reports of a possible association between exogenous oestrogens and endometrial carcinoma have increased professional reluctance to prescribe oestrogens for menopausal symptoms. This report describes the initial 50 patients who have attended a special clinic established to manage symptomatic menopausal women; common complaints included hot flushes, lack of energy, altered temperament, dyspareunia and headache. Oestrogen therapy was effective in the alleviation of symptoms and the practical aspects of oestrogen use are discussed. It is recommended that with due recognition of its potential complications, oestrogen therapy should be made available to symptomatic menopausal women, and that it requires further study in regard to its place in the long-term prophylaxis of osteoporosis.
大多数女性在绝经时会出现各种症状，但医生常常认为这些症状不值得处理。最近有报道称外源性雌激素与子宫内膜癌之间可能存在关联，这使得医生在为绝经症状开雌激素处方时更加犹豫。本报告描述了最初到一家专门诊所就诊的50例有症状的绝经女性患者；常见的主诉包括潮热、乏力、性情改变、性交困难和头痛。雌激素疗法在缓解症状方面有效，并讨论了雌激素使用的实际问题。建议在充分认识到其潜在并发症的情况下，应为有症状的绝经女性提供雌激素疗法，并且其在骨质疏松症长期预防中的作用需要进一步研究。
