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发育不良性冠状动脉疾病导致猝死。两例报告并文献复习。

Hypoplastic coronary artery disease causing sudden death. Report of two cases and review of the literature.

机构信息

Institute of Legal Medicine, Catholic University of the Sacred Heart, School of Medicine, Rome, Italy.

出版信息

Cardiovasc Pathol. 2010 Jul-Aug;19(4):e107-11. doi: 10.1016/j.carpath.2009.05.002. Epub 2009 Jul 18.

DOI:10.1016/j.carpath.2009.05.002
PMID:19616973
Abstract

Congenital coronary anomalies represent a condition often unrecognized in the living and in the dead. Investigating this condition is relevant for both clinicians and pathologists in order to identify potentially unrecognized coronary causes of sudden death. Hypoplastic coronary artery disease (HCAD) is a rare congenital abnormality reported to be associated with sudden death. We report two additional cases of previously apparently healthy people who died suddenly and were found to have HCAD at postmortem evaluation. The clinicopathologic findings are discussed along with a review of the literature.

摘要

先天性冠状动脉异常在活体和尸体中常常未被识别。为了识别潜在的未被认识的冠状动脉猝死原因,临床医生和病理学家都需要对这种情况进行调查。发育不良性冠状动脉疾病(HCAD)是一种罕见的先天性异常,据报道与猝死有关。我们报告了另外两例先前显然健康的人突然死亡,并在尸检评估时发现患有 HCAD。本文讨论了临床病理发现,并复习了文献。

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