The Krebs cycle meets the cell cycle: mitochondria and the G1-S transition.
作者信息
Finkel Toren, Hwang Paul M
机构信息
Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11825-6. doi: 10.1073/pnas.0906430106. Epub 2009 Jul 15.
Abstract
摘要
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本文引用的文献
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A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase.在G1-S期达到的线粒体高度融合状态调节细胞周期蛋白E的积累并进入S期。
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2
Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells.线粒体代谢调节小鼠胚胎干细胞的分化和畸胎瘤形成能力。
J Biol Chem. 2008 Oct 17;283(42):28506-12. doi: 10.1074/jbc.M802763200. Epub 2008 Aug 18.
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Coordination of mitochondrial bioenergetics with G1 phase cell cycle progression.线粒体生物能量学与G1期细胞周期进程的协调。
Cell Cycle. 2008 Jun 15;7(12):1782-7. doi: 10.4161/cc.7.12.6067. Epub 2008 Jun 2.
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AMPK phosphorylation of raptor mediates a metabolic checkpoint.Raptor的AMPK磷酸化介导代谢检查点。
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Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint.不同的线粒体逆行信号控制G1-S细胞周期检查点。
Nat Genet. 2008 Mar;40(3):356-61. doi: 10.1038/ng.2007.50. Epub 2008 Feb 3.
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Functions and dysfunctions of mitochondrial dynamics.线粒体动力学的功能与功能障碍。
Nat Rev Mol Cell Biol. 2007 Nov;8(11):870-9. doi: 10.1038/nrm2275.
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p53 regulates mitochondrial respiration.p53调节线粒体呼吸。
Science. 2006 Jun 16;312(5780):1650-3. doi: 10.1126/science.1126863. Epub 2006 May 25.
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Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila.果蝇终身突变揭示发育过程中线粒体对细胞周期进程的调控
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9
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint.AMP激活的蛋白激酶诱导p53依赖的代谢检查点。
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