ML Flow 检测在麻风病分类中的影响。
The influence of ML Flow test in leprosy classification.
作者信息
Grossi Maria Aparecida de Faria, Leboeuf Maria Ana Araújo, Andrade Ana Regina Coelho de, Lyon Sandra, Antunes Carlos Maurício de Figueiredo, Bührer-Sékula Samira
机构信息
Post-graduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, Federal University of Minas Gerais, MG, Brazil.
出版信息
Rev Soc Bras Med Trop. 2008;41 Suppl 2:34-8. doi: 10.1590/s0037-86822008000700008.
This is a descriptive, exploratory study correlating ML Flow, bacilloscopy and classification of paucibacillary (PB) and multibacillary (MB), involving 1,041 new leprosy cases in 13 municipalities of Minas Gerais State, from October 2002 to March 2004. Agreement between ML Flow and the classification of the number of skin lesions and bacilloscopy was moderate (K:0.51 and K:0.48, respectively); and substantial for final classification (K:0.77). From January 2000 to March 2004, the proportion of new MB cases in Minas Gerais decreased from 78.1 to 65.8%. The reduction in the percentage of MB cases was higher in health centers that participated in the ML Flow study (73.1% to 53.3%). The difference between PB and MB in the participating and non-participating health centers from January to March 2004 was statistically significant. Implementation of the ML Flow test influenced the classification of patients, suggesting a direct and beneficial impact on patient treatment and the control of the leprosy endemic in Minas Gerais, Brazil.
这是一项描述性探索性研究，将多层流式细胞术（ML Flow）、细菌学检查与少菌型（PB）和多菌型（MB）分类相关联，涉及2002年10月至2004年3月期间米纳斯吉拉斯州13个市的1041例新麻风病例。ML Flow与皮肤损害数量分类及细菌学检查之间的一致性为中等（K值分别为0.51和0.48）；最终分类的一致性较高（K值为0.77）。2000年1月至2004年3月，米纳斯吉拉斯州新多菌型病例的比例从78.1%降至65.8%。参与ML Flow研究的卫生中心多菌型病例百分比的下降幅度更大（从73.1%降至53.3%）。2004年1月至3月，参与和未参与的卫生中心中少菌型和多菌型之间的差异具有统计学意义。ML Flow检测的实施影响了患者分类，表明对巴西米纳斯吉拉斯州患者治疗和麻风病流行控制有直接有益影响。
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