Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloníki, Greece.
Acta Diabetol. 2010 Dec;47 Suppl 1:83-9. doi: 10.1007/s00592-009-0136-1. Epub 2009 Jul 18.
The aim of this study was to assess whether the levels of physical activity before and during early pregnancy are associated with the prevalence of gestational diabetes mellitus (GDM). The study group included 160 puerperas. Among them, 40 (25%) diagnosed as having GDM during their recent pregnancy, whereas the remaining 120 (75%) served as controls. The international physical activity questionnaire (IPAQ-Greek version) was applied twice, in an attempt to estimate the level of physical activity before and during early pregnancy. Women who were "inactive" before or during early pregnancy had odds ratio (OR) 7.9 [95% confidence interval (CI) 3.7-16.56] and 1.3 (95% CI 1.2-1.4) of developing GDM, compared to "minimally active" or "active" women, respectively. Pregnancy resulted in a decrease in the level of physical activity (P < 0.005) during early pregnancy, independently of the diagnosis of GDM and morbidity during early pregnancy. We conclude that physical inactivity before and during early pregnancy is associated with increased risk for developing GDM in late pregnancy.
本研究旨在评估妊娠早期前后的体力活动水平与妊娠糖尿病（GDM）的患病率之间是否存在关联。研究组包括 160 名产妇。其中，40 名（25%）在最近的妊娠期间被诊断为患有 GDM，而其余 120 名（75%）作为对照组。应用国际体力活动问卷（IPAQ-Greek 版本）两次，以尝试估计妊娠前和妊娠早期的体力活动水平。与“低活跃”或“活跃”的女性相比，妊娠前或妊娠早期“不活跃”的女性发生 GDM 的比值比（OR）分别为 7.9（95%置信区间（CI）3.7-16.56）和 1.3（95%CI 1.2-1.4）。与 GDM 的诊断和妊娠早期的发病率无关，妊娠导致妊娠早期体力活动水平下降（P<0.005）。我们得出结论，妊娠前和妊娠早期的体力活动不足与妊娠晚期发生 GDM 的风险增加有关。
