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经肛门复发瘘手术后的生活质量。

Quality of life following surgery for recurrent fistula-in-ano.

机构信息

Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

出版信息

Tech Coloproctol. 2009 Sep;13(3):215-7. doi: 10.1007/s10151-009-0517-z. Epub 2009 Jul 18.

Abstract

BACKGROUND

The management of fistula-in-ano remains a major surgical challenge and carries a significant morbidity affecting the quality of life (QOL) due to the disease and repeated operations. The aim of the study was to assess the QOL before and after successful surgical treatment of recurrent fistula-in-ano using the gastrointestinal quality of life index (GIQLI) which is a validated instrument consisting of 36 questions for measuring quality of life in patients with gastrointestinal disorders including fistula-in-ano.

METHODS

All patients who underwent successful surgical treatment for recurrent fistula-in-ano over a period of 12 months were prospectively analysed using the GIQLI preoperatively and after a minimum of 18 months (mean, 24; range, 18-30) after complete cure following surgery. The difference in the QOL scores were analysed using Wilcoxon rank test.

RESULTS

In the 21 patients recruited for the study there was a significant (P < 0.01) difference between the average preoperative (97.02) and postoperative (116.14) GIQLI scores. Of all the areas assessed by the GIQLI questionnaire, greater statistical significance was seen in areas of emotions (P < 0.01), social integration (P < 0.01) and effects of treatment (P < 0.01).

CONCLUSIONS

Recurrent fistula-in-ano significantly affects the patients' QOL, and also, successful surgery results in significantly improved long-term QOL. This improvement shows the need for those patients with fistula-in-ano to be subjected to further surgery despite the possible risk of anal incontinence.

摘要

背景

肛瘘的治疗仍然是一个主要的外科挑战,由于疾病和反复手术,其发病率很高,严重影响生活质量(QOL)。本研究的目的是使用胃肠道生活质量指数(GIQLI)评估成功治疗复发性肛瘘患者的 QOL,GIQLI 是一种经过验证的工具,由 36 个问题组成,用于测量包括肛瘘在内的胃肠道疾病患者的生活质量。

方法

在 12 个月的时间内,对接受成功手术治疗复发性肛瘘的所有患者进行前瞻性分析,在手术后至少 18 个月(平均 24 个月;范围 18-30 个月)进行 GIQLI 术前和术后评估。使用 Wilcoxon 秩检验分析 QOL 评分的差异。

结果

在 21 名入组研究的患者中,GIQLI 评分的平均术前(97.02)和术后(116.14)评分有显著差异(P < 0.01)。在 GIQLI 问卷评估的所有领域中,情绪(P < 0.01)、社会融合(P < 0.01)和治疗效果(P < 0.01)方面的统计学意义更大。

结论

复发性肛瘘显著影响患者的 QOL,而成功的手术可显著改善长期 QOL。这种改善表明,即使存在肛门失禁的可能风险,患有肛瘘的患者也需要进一步接受手术治疗。

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