Dietrich C F, Hirche T O, Ott M, Ignee A
Department of Internal Medicine II, Caritas Hospital, Bad Mergentheim, Germany.
Endoscopy. 2009 Aug;41(8):718-20. doi: 10.1055/s-0029-1214866. Epub 2009 Jul 17.
Endoscopic ultrasound (EUS) elastography distinguishes tissues on the basis of their specific consistency. The preoperative diagnosis of autoimmune pancreatitis (AIP) is of the utmost importance in order to avoid surgery. The aim of this prospective evaluation of five patients was to investigate the role of this new technique in the characterization of mass lesions caused by AIP, with histology as the gold standard. All five patients with AIP presented with a characteristic stiff elastographic pattern not only of the mass lesion but also of the surrounding pancreatic parenchyma, which was not found in 17 patients with ductal adenocarcinoma and 10 healthy subjects. EUS elastography of the pancreas shows a typical and unique finding with homogenous stiffness of the whole organ, and this distinguishes AIP from the circumscribed mass lesion in ductal adenocarcinoma.
内镜超声（EUS）弹性成像根据组织的特定硬度来区分组织。自身免疫性胰腺炎（AIP）的术前诊断对于避免手术至关重要。这项对五名患者的前瞻性评估旨在以组织学为金标准，研究这项新技术在AIP所致肿块病变特征描述中的作用。所有五名AIP患者不仅肿块病变呈现出特征性的硬弹性成像模式，其周围胰腺实质也是如此，而17名导管腺癌患者和10名健康受试者中均未发现这种情况。胰腺的EUS弹性成像显示出整个器官硬度均匀这一典型且独特的表现，这将AIP与导管腺癌中的局限性肿块病变区分开来。
