Harindranath Sidharth, Sundaram Sridhar
Department of Gastroenterology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai 400012, India.
Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai 400012, India.
Diagnostics (Basel). 2023 May 19;13(10):1797. doi: 10.3390/diagnostics13101797.
Chronic pancreatitis (CP) is a known risk factor for pancreatic cancer. CP may present with an inflammatory mass, and differentiation from pancreatic cancer is often difficult. Clinical suspicion of malignancy dictates a need for further evaluation for underlying pancreatic cancer. Imaging modalities remain the mainstay of evaluation for a mass in background CP; however, they have their shortcomings. Endoscopic ultrasound (EUS) has become the go-to investigation. Adjunct modalities such as contrast-harmonic EUS and EUS elastography, as well as EUS-guided sampling using newer-generation needles are useful in differentiating inflammatory from malignant masses in the pancreas. Paraduodenal pancreatitis and autoimmune pancreatitis often masquerade as pancreatic cancer. In this narrative review, we discuss the various modalities used to differentiate inflammatory from malignant masses of the pancreas.
慢性胰腺炎（CP）是胰腺癌已知的危险因素。CP可能表现为炎性肿块，与胰腺癌进行鉴别往往很困难。临床怀疑恶性肿瘤提示需要对潜在的胰腺癌进行进一步评估。影像学检查仍是评估合并CP的肿块的主要手段；然而，它们也有其不足之处。内镜超声（EUS）已成为首选的检查方法。诸如对比谐波EUS、EUS弹性成像等辅助检查方法，以及使用新一代穿刺针进行的EUS引导下采样，对于鉴别胰腺炎性肿块和恶性肿块很有用。十二指肠旁胰腺炎和自身免疫性胰腺炎常伪装成胰腺癌。在这篇叙述性综述中，我们讨论了用于鉴别胰腺炎性肿块和恶性肿块的各种检查方法。
