一名患有唐氏综合征的女孩同时患有1型糖尿病、甲状腺功能减退症和乳糜泻——一种罕见的关联。

Type 1 diabetes mellitus, hypothyroidism and celiac disease in a girl with Down's syndrome--a rare association.

作者信息

Santos Raquel, Correia Susana, Pereira Carla, Sampaio Lurdes

机构信息

Department of Pediatric Endocrinology, Hospital de Santa Maria, Lisbon, Portugal.

出版信息

J Pediatr Endocrinol Metab. 2009 May;22(5):455-7. doi: 10.1515/jpem.2009.22.5.455.

DOI:10.1515/jpem.2009.22.5.455

PMID:19618665

Abstract

The prevalence of comorbilities such as type 1 diabetes mellitus (DM1), celiac disease and hypothyroidism is higher in Down's syndrome (DS) compared with the general population; however, the association of all these pathologies is rare. We report a girl with DS, now 7 years old, who developed DM1, hypothyroidism and celiac disease at different times. The authors consider important that follow-up programs for patients with DS include screening for these pathologies.

摘要

与普通人群相比，唐氏综合征（DS）患者中1型糖尿病（DM1）、乳糜泻和甲状腺功能减退等合并症的患病率更高；然而，所有这些病症同时出现的情况很少见。我们报告了一名现年7岁的DS女童，她在不同时期分别患上了DM1、甲状腺功能减退和乳糜泻。作者认为，DS患者的随访计划应包括对这些病症的筛查，这一点很重要。