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[口腔扁平苔藓:疑问与证据]

[The oral lichen planus: doubts and evidence].

作者信息

Tar Ildikó, Márton Ildikó

机构信息

Debreceni Egyetem OEC, Fogorvostudományi Kar, Parodontológiai Tanszék, Restauratív Fogászati Tanszék, Debrecen.

出版信息

Fogorv Sz. 2009 Jun;102(3):103-9.

Abstract

Oral lichen planus (OLP) is the oral mucosal form of the lichen ruber planus disease. Its diagnostics is not an easy task. Difficulties exist in diagnosing OLP because there are no fully accepted criteria (neither clinical, nor histological) of the disease. Its etiopathogenesis is also not fully understood. Previous studies concentrated on local factors of the disease such as bad oral hygiene, bad dental condition, and smoking. These studies established that OLP is relatively independent from these factors. Besides local factors, chronic systemic diseases like diabetes and hepatitis of HCV origin were examined. Studies on the parallel occurrence of the OLP with systemic diseases in different populations led to contradictory results. This might strengthen the fact that etiological factors causing the OLP, or worsening the OLP, or playing a role in malignant changes are not the same. Our review would like to provide possible answers to questions concerning OLP.

摘要

口腔扁平苔藓(OLP)是扁平苔藓病的口腔黏膜形式。其诊断并非易事。诊断OLP存在困难,因为目前尚无该疾病被完全认可的标准(无论是临床标准还是组织学标准)。其病因发病机制也尚未完全明确。以往的研究集中在该疾病的局部因素,如口腔卫生不良、牙齿状况不佳和吸烟。这些研究表明OLP相对独立于这些因素。除了局部因素外,还对慢性全身性疾病如糖尿病和丙型肝炎病毒引起的肝炎进行了研究。关于不同人群中OLP与全身性疾病同时发生的研究结果相互矛盾。这可能强化了这样一个事实,即导致OLP、使OLP恶化或在恶性变化中起作用的病因并不相同。我们的综述旨在为有关OLP的问题提供可能的答案。

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