Morris M D, Jones T D, Young R W
Engineering Physics and Mathematics Division, Oak Ridge National Laboratory, Tennessee 37831-6367.
Radiat Res. 1991 Dec;128(3):267-75.
The rate coefficients in the model of cell kinetics and mortality introduced by Jones et al. (Radiat. Res. 128, 258-266 (1991)) are estimated using mortality data from several mouse experiments. The evaluated model fits data from a large variety of prompt, protracted, and fractionated irradiations with 250-k Vp X rays with good fidelity. Although the maximum-likelihood estimates are not unique, all estimates lead to greater cell survival than that observed in in vitro experiments on nonterminally differentiated reproducing cells from the marrow.
琼斯等人（《辐射研究》第128卷，第258 - 266页（1991年））提出的细胞动力学和死亡率模型中的速率系数，是利用多个小鼠实验的死亡率数据估算得出的。经评估，该模型能很好地拟合来自各种250 kVp X射线的即时、持续和分次照射的数据。尽管最大似然估计并非唯一，但所有估计得出的细胞存活率都高于对来自骨髓的未终末分化增殖细胞进行的体外实验中所观察到的存活率。
