Morris M D, Jones T D, Young R W
Engineering Physics and Mathematics Division, Oak Ridge National Laboratory, Tennessee 37831-6367.
Radiat Res. 1993 Sep;135(3):320-31.
Rate coefficients in the model of cell kinetics and mortality introduced by Jones et al. (Radiat. Res. 128, 258-266, 1991) are estimated using mortality data from 27 animal experiments. Adjustments are made for the six species and three nominal classes of gamma radiation represented in these studies. The model fits most of the mortality data quite well when the rate coefficient representing cellular proliferation is fitted to individual species and each of the other coefficients is given a single value across the entire data set. Results are qualitatively similar to those reported by Morris et al. (Radiat. Res. 128, 267-275, 1991) who estimated the rate coefficients from a limited number of mouse studies involving only 250 kVp X rays. As in the earlier study, estimates here lead to greater cell survival than is observed for marrow cells in the amplification division compartment.
琼斯等人（《辐射研究》128卷，第258 - 266页，1991年）提出的细胞动力学和死亡率模型中的速率系数，是利用27项动物实验的死亡率数据估算得出的。针对这些研究中所代表的6个物种和3种标称等级的γ辐射进行了调整。当将代表细胞增殖的速率系数拟合到各个物种，而其他每个系数在整个数据集上都赋予一个单一值时，该模型能很好地拟合大多数死亡率数据。结果在定性上与莫里斯等人（《辐射研究》128卷，第267 - 275页，1991年）所报告的相似，他们从仅涉及250 kVp X射线的有限数量的小鼠研究中估算速率系数。与早期研究一样，此处的估算结果显示细胞存活率高于在扩增分裂区室中观察到的骨髓细胞存活率。
