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人博卡病毒:儿童严重哮喘加重的一个病因

Human bocavirus: a cause of severe asthma exacerbation in children.

作者信息

Vallet Christelle, Pons-Catalano Charlotte, Mandelcwajg Alexis, Wang Andrew, Raymond Josette, Lebon Pierre, Gendrel Dominique

机构信息

Pediatric Unit, Paris Descartes University and AP-HP Saint Vincent de Paul-Cochin Hospital, Paris, France.

出版信息

J Pediatr. 2009 Aug;155(2):286-8. doi: 10.1016/j.jpeds.2009.01.069.

Abstract

Real-time polymerase chain reaction for human bocavirus (HBoV) was performed in nasopharyngeal aspirate specimens from 166 children over 2 years of age hospitalized for severe asthma exacerbation. Whereas HBoV was detected in 21 of these children (13%), it was found in only 1 of 50 ambulatory children with stable asthma (2%), suggesting a major role of HBoV in acute exacerbations in asthmatic children.

摘要

对166名因重度哮喘急性发作而住院的2岁以上儿童的鼻咽抽吸物样本进行了人博卡病毒(HBoV)的实时聚合酶链反应检测。在这些儿童中,有21名(13%)检测到HBoV,而在50名哮喘病情稳定的门诊儿童中,只有1名(2%)检测到该病毒,这表明HBoV在哮喘儿童急性发作中起主要作用。

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