Fanjul-Vélez Félix, Romanov Oleg G, Arce-Diego José Luis
Applied Optical Techniques Group, TEISA Department, University of Cantabria, Santander, Spain.
Comput Biol Med. 2009 Sep;39(9):810-7. doi: 10.1016/j.compbiomed.2009.06.009. Epub 2009 Jul 19.
Temperature prediction in biological tissues irradiated by an optical source is frequently required in some medical applications, like Thermotherapy, Hyperthermia or tissue ablation. In this work we propose a new numerical approach to solve the bio-heat equation. It is based on the two steps 3D modified Du Fort-Frankel algorithm, which allows a better convergence, more accuracy and a faster computation than previous numerical methods developed by other authors. The model also includes adaptive spatial mesh and time step refinement. These improved results for opto-thermal temperature distribution could be used for choosing appropriate laser treatment parameters in medical praxis.
在一些医学应用中，如热疗法、高温治疗或组织消融，经常需要预测生物组织在光源照射下的温度。在这项工作中，我们提出了一种新的数值方法来求解生物热方程。它基于两步三维修正的杜福特-弗兰克尔算法，与其他作者以前开发的数值方法相比，该算法具有更好的收敛性、更高的精度和更快的计算速度。该模型还包括自适应空间网格和时间步长细化。这些关于光热温度分布的改进结果可用于在医学实践中选择合适的激光治疗参数。
