Zhang Chuan, Zha Dao-Gang, DU Rong-Sheng, Hu Feng, Li Sheng-Hui, Wu Xiao-Yuan, Liu Yi-Li
Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2009 Jul;29(7):1333-6.
To assess the value of velocity vector imaging (VVI) and quantitative tissue velocity imaging (QTVI) in assessing left ventricular diastolic function of the dogs with acute myocardial ischemia.
Six healthy mongrel dogs were subjected to ligation of the left circumflex artery or left anterior descending artery to induce coronary artery stenosis of varying degrees. The mean peak diastolic velocity (Em) of the ventricular walls around the mitral annulus was recorded with VVI or QTVI in the coronary blood flow. The left ventricular end diastolic pressure (LVEDP) was measured with pigtail catheter in the left ventricle.
As the coronary blood flow decreased, LVEDP was gradually increased, and Em measured by VVI or QTVI were also gradually decreased. A good linear correlation was shown between Em measured by VVI or QTVI and LVEDP (r=-0.834, P<0.001, and r=-0.68, P<0.001, respectively). A significant difference was observed in the correlation coefficient between VVI and QTVI (Z=2.625, P=0.0087).
VVI and QTVI both provide good noninvasive means for measuring left ventricular diastolic function. VVI, a new echocardiographic modality without angular dependence, is better than QTVI in evaluating left ventricular diastolic function.
评估速度向量成像（VVI）和定量组织速度成像（QTVI）在评估急性心肌缺血犬左心室舒张功能中的价值。
对6只健康杂种犬进行左旋支动脉或左前降支动脉结扎，以诱导不同程度的冠状动脉狭窄。在冠状动脉血流中，用VVI或QTVI记录二尖瓣环周围心室壁的平均舒张期峰值速度（Em）。用猪尾导管测量左心室内的左心室舒张末期压力（LVEDP）。
随着冠状动脉血流减少，LVEDP逐渐升高，VVI或QTVI测量的Em也逐渐降低。VVI或QTVI测量的Em与LVEDP之间呈良好的线性相关（r分别为-0.834，P<0.001和r为-0.68，P<0.001）。VVI与QTVI之间的相关系数存在显著差异（Z=2.625，P=0.0087）。
VVI和QTVI均为测量左心室舒张功能提供了良好的非侵入性方法。VVI是一种新的无角度依赖性的超声心动图检查方法，在评估左心室舒张功能方面优于QTVI。
