Zhang Chuan, Zha Dao-Gang, Liu Yi-Li, Wang Peng, Hou Yu-Qing, Xiu Jian-Cheng, Wang Yue-Gang, Zhou Zhong-Jiang
Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Nov;37(11):1026-9.
To validate the efficacy of velocity vector imaging (VVI) and quantitative tissue velocity imaging (QTVI) for evaluating left ventricular diastolic function.
Fifty-one patients underwent left heart catheterization were included in this study. Mean of peak early diastolic velocity (Em), EF and the ratio of early (E) to late (A) mitral valve flow velocity (E/A) were measured by echocardiography and the ratio of E to Em (E/Em) was calculated. Left ventricular end diastolic pressure (LVEDP) was measured during catheterization examination.
E/Em derived from VVI or QTVI was significantly correlated with LVEDP (r = 0.808, P < 0.01 and r = 0.692, P < 0.01, respectively) and the correlation coefficient between VVI and LVEDP was significantly higher than that between QTVI and LVEDP (Z = 2.246, P = 0.025). Em derived from VVI and QTVI also negatively correlated with LVEDP (r = -0.740, P < 0.01 and r = -0.567, P < 0.01) and the correlation coefficient between VVI and LVEDP was significantly higher than that between QTVI and LVEDP (Z = 2.595, P = 0.009). However, there was no correlation between E/A and LVEDP (r = 0.117, P = 0.415).
E/Em and Em derived from VVI and QTVI are valuable parameters for evaluating LV diastolic function.
验证速度向量成像（VVI）和定量组织速度成像（QTVI）评估左心室舒张功能的有效性。
本研究纳入51例行左心导管检查的患者。通过超声心动图测量舒张早期峰值速度（Em）、射血分数（EF）的平均值以及二尖瓣血流速度早期（E）与晚期（A）的比值（E/A），并计算E与Em的比值（E/Em）。在导管检查期间测量左心室舒张末期压力（LVEDP）。
VVI或QTVI得出的E/Em与LVEDP显著相关（r分别为0.808，P<0.01和0.692，P<0.01），且VVI与LVEDP之间的相关系数显著高于QTVI与LVEDP之间的相关系数（Z = 2.246，P = 0.025）。VVI和QTVI得出的Em也与LVEDP呈负相关（r分别为-0.740，P<0.01和-0.567，P<0.01），且VVI与LVEDP之间的相关系数显著高于QTVI与LVEDP之间的相关系数（Z = 2.595，P = 0.009）。然而，E/A与LVEDP之间无相关性（r = 0.117，P = 0.415）。
VVI和QTVI得出的E/Em和Em是评估左心室舒张功能的有价值参数。
