Serratrice G, Pellissier J F, Desnuelle C, Pouget J
Clinique des Maladies du Système Nerveux et de l'appareil Locomoteur, CHU La Timone, Marseille.
Rev Neurol (Paris). 1991;147(6-7):474-5.
The authors report the clinical signs and histological findings in 62 patients with ocular myopathies divided into two groups: (a) ocular myopathies with mitochondrial abnormalities, themselves divided into pure (19 cases) or progressive (15 cases) ophthalmoplegia, and multisystemic myopathies (14 cases); (2) oculopharyngeal myopathies (15 cases) in elderly subjects, with constant intranuclear tubulofilamentous inclusions. Among myopathies with mitochondrial abnormalities, ocular forms with a favourable prognosis coexisted with earlier and more severe multisystemic lesions.
作者报告了62例眼肌病患者的临床体征和组织学发现,这些患者被分为两组:(a) 伴有线粒体异常的眼肌病,其本身又分为单纯性(19例)或进行性(15例)眼肌麻痹,以及多系统肌病(14例);(2) 老年患者的眼咽型肌病(15例),伴有恒定的核内管状细丝包涵体。在伴有线粒体异常的肌病中,预后良好的眼肌型与更早、更严重的多系统病变并存。