Stotka J L, Rupp M E, Meier F A, Markowitz S M
Department of Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond.
Rev Infect Dis. 1991 Sep-Oct;13(5):837-41. doi: 10.1093/clinids/13.5.837.
Neisseria mucosa is a species of gram-negative cocci that has a characteristic mucoid, adherent colonial morphology and includes pigmented and nonpigmented morphotypes. The ability of N. mucosa to reduce nitrates distinguishes it from other Neisseria species. N. mucosa is part of the normal human nasopharyngeal flora and infrequently causes human infections, including meningitis. We report a unique case of a patient with a cerebrospinal fluid shunt infection due to N. mucosa and review five other reports of cases of meningitis caused by this organism. Seven additional previously reported cases of presumed N. mucosa meningitis have been excluded from this review on the basis of the current criteria for identification of the organism. In the reports of established cases, female infants and children who often had predisposing conditions predominate. Although the outcome for such patients has been favorable, no clinical or laboratory findings are helpful in distinguishing meningitis due to N. mucosa from that due to other bacteria.
黏液奈瑟菌是一种革兰氏阴性球菌,具有典型的黏液样、黏附性菌落形态,包括有色素和无色素的形态型。黏液奈瑟菌还原硝酸盐的能力使其与其他奈瑟菌属菌种相区别。黏液奈瑟菌是人类正常鼻咽部菌群的一部分,很少引起人类感染,包括脑膜炎。我们报告了一例因黏液奈瑟菌导致脑脊液分流感染的独特病例,并回顾了另外五例由该菌引起的脑膜炎病例报告。根据目前该菌种的鉴定标准,另外七例先前报告的疑似黏液奈瑟菌脑膜炎病例已被排除在本综述之外。在确诊病例的报告中,经常有易感因素的女婴和儿童占多数。尽管此类患者的预后良好,但没有临床或实验室检查结果有助于区分黏液奈瑟菌引起的脑膜炎与其他细菌引起的脑膜炎。