Gentile G, Venditti M, Micozzi A, Caprioli A, Donelli G, Tirindelli C, Meloni G, Arcese W, Martino P
Dipartimento di Biopatologia Umana, Università La Sapienza, Rome, Italy.
Rev Infect Dis. 1991 Sep-Oct;13(5):842-6. doi: 10.1093/clinids/13.5.842.
The clinical features of cryptosporidial infection in 20 patients with hematologic malignancies were assessed. Five patients had severe diarrhea, 10 had moderate diarrhea, and five were asymptomatic carriers of Cryptosporidium. Extraintestinal cryptosporidiosis with pulmonary involvement was observed in one case and relapse of cryptosporidiosis in four. All but one patient recovered from cryptosporidiosis whether or not spiramycin was administered. Cryptosporidiosis in T cell-depleted recipients of allogeneic bone marrow transplants did not appear more severe than that in patients undergoing autologous bone marrow transplantation or conventional chemotherapy.
对20例血液系统恶性肿瘤患者隐孢子虫感染的临床特征进行了评估。5例患者出现严重腹泻，10例有中度腹泻，5例为隐孢子虫无症状携带者。观察到1例合并肺部受累的肠外隐孢子虫病，4例隐孢子虫病复发。除1例患者外，无论是否使用螺旋霉素，所有患者的隐孢子虫病均痊愈。在接受异基因骨髓移植且T细胞耗竭的受者中，隐孢子虫病似乎并不比接受自体骨髓移植或传统化疗的患者更严重。
